Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury

Mitochondrial dysfunction underlies many prevalent diseases including heart disease arising from acute ischemia/reperfusion (I/R) injury. Here, we demonstrate that mitophagy, which selectively removes damaged or unwanted mitochondria, regulated mitochondrial quality and quantity in vivo. Hypoxia ind...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Zhang, Weilin, Ren, He, Xu, Chunling, Zhu, Chongzhuo, Wu, Hao, Liu, Dong, Wang, Jun, Liu, Lei, Li, Wei, Ma, Qi, Du, Lei, Zheng, Ming, Zhang, Chuanmao, Liu, Junling, Chen, Quan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2016
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214169/
https://ncbi.nlm.nih.gov/pubmed/27995894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21407
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia