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Role of the BrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice

The BrafV637E mutation is frequently reported in mouse hepatic tumors, depending on the mouse strain, and corresponds to the human BrafV600E mutation. In this study, we detected the BrafV637E mutation by whole‐exome analysis in 4/4 hepatic tumors induced by neonatal treatment with diethylnitrosamine...

詳細記述

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書誌詳細
出版年:Mol Carcinog
主要な著者: Yamamoto, Masahiro, Tanaka, Hiroki, Xin, Bing, Nishikawa, Yuji, Yamazaki, Kosuke, Shimizu, Keiko, Ogawa, Katsuhiro
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214095/
https://ncbi.nlm.nih.gov/pubmed/27253992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22510
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