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Role of the BrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice

The BrafV637E mutation is frequently reported in mouse hepatic tumors, depending on the mouse strain, and corresponds to the human BrafV600E mutation. In this study, we detected the BrafV637E mutation by whole‐exome analysis in 4/4 hepatic tumors induced by neonatal treatment with diethylnitrosamine...

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Bibliografiske detaljer
Udgivet i:Mol Carcinog
Main Authors: Yamamoto, Masahiro, Tanaka, Hiroki, Xin, Bing, Nishikawa, Yuji, Yamazaki, Kosuke, Shimizu, Keiko, Ogawa, Katsuhiro
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214095/
https://ncbi.nlm.nih.gov/pubmed/27253992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22510
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