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Role of the BrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice

The BrafV637E mutation is frequently reported in mouse hepatic tumors, depending on the mouse strain, and corresponds to the human BrafV600E mutation. In this study, we detected the BrafV637E mutation by whole‐exome analysis in 4/4 hepatic tumors induced by neonatal treatment with diethylnitrosamine...

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發表在:Mol Carcinog
Main Authors: Yamamoto, Masahiro, Tanaka, Hiroki, Xin, Bing, Nishikawa, Yuji, Yamazaki, Kosuke, Shimizu, Keiko, Ogawa, Katsuhiro
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214095/
https://ncbi.nlm.nih.gov/pubmed/27253992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22510
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