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Iridium-Catalyzed Regio- and Enantioselective Allylic Substitution of Trisubstituted Allylic Electrophiles

The first Ir-catalyzed enantioselective allylation of trisubstituted allylic electrophiles has been developed. Through modification of the leaving group of allylic electrophiles, we found that trisubstituted allylic phosphates are suitable electrophiles for asymmetric allylation. The reaction of all...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Chen, Ming, Hartwig, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213737/
https://ncbi.nlm.nih.gov/pubmed/27531137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607053
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