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Iridium-Catalyzed Regio- and Enantioselective Allylic Substitution of Trisubstituted Allylic Electrophiles

The first Ir-catalyzed enantioselective allylation of trisubstituted allylic electrophiles has been developed. Through modification of the leaving group of allylic electrophiles, we found that trisubstituted allylic phosphates are suitable electrophiles for asymmetric allylation. The reaction of all...

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Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Chen, Ming, Hartwig, John F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213737/
https://ncbi.nlm.nih.gov/pubmed/27531137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607053
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