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Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain

MscS (mechanosensitive channel of small conductance) is ubiquitously found among bacteria and plays a major role in avoiding cell lysis upon rapid osmotic downshock. The gating of MscS is modulated by voltage, but little is known about how MscS senses membrane potential. Three arginine residues (Arg...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Nomura, Takeshi, Sokabe, Masahiro, Yoshimura, Kenjiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213669/
https://ncbi.nlm.nih.gov/pubmed/28101504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2401657
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