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Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain

MscS (mechanosensitive channel of small conductance) is ubiquitously found among bacteria and plays a major role in avoiding cell lysis upon rapid osmotic downshock. The gating of MscS is modulated by voltage, but little is known about how MscS senses membrane potential. Three arginine residues (Arg...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Nomura, Takeshi, Sokabe, Masahiro, Yoshimura, Kenjiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213669/
https://ncbi.nlm.nih.gov/pubmed/28101504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2401657
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