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Structural Changes in the Cytoplasmic Domain of the Mechanosensitive Channel MscS During Opening

The bacterial mechanosensitive channel MscS forms a homoheptamer of subunits composed of a transmembrane (TM) domain and a large cytoplasmic (CP) domain. Recent studies suggest that a lateral expansion of the TM domain, structural change in the CP domain, and TM-CP interactions are essential to open...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Machiyama, Hiroaki, Tatsumi, Hitoshi, Sokabe, Masahiro
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726311/
https://ncbi.nlm.nih.gov/pubmed/19686652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.021
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