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Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice

Collagens carry hydroxylysine residues that act as attachment sites for carbohydrate units and are important for the stability of crosslinks but have been regarded as nonessential for vertebrate survival. We generated mice with targeted inactivation of the gene for one of the three lysyl hydroxylase...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rautavuoma, Kati, Takaluoma, Kati, Sormunen, Raija, Myllyharju, Johanna, Kivirikko, Kari I., Soininen, Raija
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15377789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404966101
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