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Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice
Collagens carry hydroxylysine residues that act as attachment sites for carbohydrate units and are important for the stability of crosslinks but have been regarded as nonessential for vertebrate survival. We generated mice with targeted inactivation of the gene for one of the three lysyl hydroxylase...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521128/ https://ncbi.nlm.nih.gov/pubmed/15377789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404966101 |
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