Nalaganje...
Single-nucleotide polymorphism discovery by targeted DNA photocleavage
Single-nucleotide polymorphisms are the largest source of genetic variation in humans. We report a method for the discovery of single-nucleotide polymorphisms within genomic DNA. Pooled genomic samples are amplified, denatured, and annealed to generate mismatches at polymorphic DNA sites. Upon photo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521117/ https://ncbi.nlm.nih.gov/pubmed/15383659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406169101 |
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