Toll‐Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells

BACKGROUND: We previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll‐like receptors (TLRs) TLR2, TLR4, and TLR9 expressed by B1a cell...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Hosseini, Hamid, Li, Yi, Kanellakis, Peter, Tay, Christopher, Cao, Anh, Liu, Edgar, Peter, Karlheinz, Tipping, Peter, Toh, Ban‐Hock, Bobik, Alex, Kyaw, Tin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210362/
https://ncbi.nlm.nih.gov/pubmed/27930350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002947
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