Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE(−/−) Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE(−/−) mice. Here, we examined the development of atherosclerosis in BAFF-R deficient ApoE(−/−) mice because B2 cells but not B1a cells are selectively depleted in BAFF-R def...

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Detalhes bibliográficos
Main Authors: Kyaw, Tin, Tay, Christopher, Hosseini, Hamid, Kanellakis, Peter, Gadowski, Tahlia, MacKay, Fabeinne, Tipping, Peter, Bobik, Alex, Toh, Ban-Hock
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251583/
https://ncbi.nlm.nih.gov/pubmed/22238605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029371
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