Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response

BACKGROUND: Prophylactic and therapeutic vaccines often depend upon a strong activation of the innate immune system to drive a potent adaptive immune response, often mediated by a strong adjuvant. For a number of adjuvants immunological readouts may not be consistent across species. METHODS: In this...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Transl Med
Main Authors: Edwards, Darin K., Jasny, Edith, Yoon, Heesik, Horscroft, Nigel, Schanen, Brian, Geter, Tanya, Fotin-Mleczek, Mariola, Petsch, Benjamin, Wittman, Vaughan
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210268/
https://ncbi.nlm.nih.gov/pubmed/28049494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1111-6
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla