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mRNA: A Novel Avenue to Antibody Therapy?

First attempts to use exogenous mRNA for protein expression in vivo were made more than 25 years ago. However, widespread appreciation of in vitro transcribed mRNA as a powerful technology for supplying therapeutic proteins to the body has evolved only during the past few years. Various approaches t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther
Prif Awduron: Schlake, Thomas, Thran, Moritz, Fiedler, Katja, Heidenreich, Regina, Petsch, Benjamin, Fotin-Mleczek, Mariola
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453519/
https://ncbi.nlm.nih.gov/pubmed/30885573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.03.002
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