Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy

Autophagy is a process delivering cytoplasmic components to lysosomes for degradation. Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic proteins. How secretory autophagy diverges from degradative autophagy remains unclear. Here we show that in response to lysos...

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Pubblicato in:EMBO J
Autori principali: Kimura, Tomonori, Jia, Jingyue, Kumar, Suresh, Choi, Seong Won, Gu, Yuexi, Mudd, Michal, Dupont, Nicolas, Jiang, Shanya, Peters, Ryan, Farzam, Farzin, Jain, Ashish, Lidke, Keith A, Adams, Christopher M, Johansen, Terje, Deretic, Vojo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210154/
https://ncbi.nlm.nih.gov/pubmed/27932448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695081
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