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TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

The present paradigms of selective autophagy in mammalian cells cannot fully explain the specificity and selectivity of autophagic degradation. In this paper, we report that a subset of tripartite motif (TRIM) proteins act as specialized receptors for highly specific autophagy (precision autophagy)...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Kimura, Tomonori, Jain, Ashish, Choi, Seong Won, Mandell, Michael A., Schroder, Kate, Johansen, Terje, Deretic, Vojo
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576868/
https://ncbi.nlm.nih.gov/pubmed/26347139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503023
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