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TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction

The tripartite motif protein family (TRIM) constitutes a class of immune-regulated proteins with antiviral, immune, cancer, and other properties reminiscent of those ascribed to autophagy. We show that TRIMs have dual roles in autophagy: as regulators and as cargo receptors. As regulators, TRIMs nuc...

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Detalhes bibliográficos
Publicado no:Autophagy
Principais autores: Mandell, Michael A, Kimura, Tomonori, Jain, Ashish, Johansen, Terje, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502693/
https://ncbi.nlm.nih.gov/pubmed/25587751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.984278
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