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YAP needs Nemo to guide a Hippo
The Hippo growth control pathway coordinates cell proliferation, death, differentiation and stemness through regulatory phosphorylation of the YAP proto‐oncoprotein, a major nuclear effector of Hippo signalling. In particular, YAP phosphorylation on Ser127 can promote inhibitory 14‐3‐3 interactions...
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Publicado no: | EMBO Rep |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5210086/ https://ncbi.nlm.nih.gov/pubmed/27979976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643622 |
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