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Multiple roles for the hippo effector yap in gut regeneration and cancer initiation
The Hippo signaling effector Yes-associated protein (Yap) is known for its potent control of tissue growth. Our recent work now shows that Yap promotes regeneration in the intestine by reprogramming intestinal stem cells and blocking their terminal differentiation. Similarly, in tumor-initiating cel...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Cell Oncol |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Taylor & Francis
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909447/ https://ncbi.nlm.nih.gov/pubmed/27314094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1143992 |
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