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Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions

The Hippo signal transduction cascade controls cell growth, proliferation, and death, all of which are frequently deregulated in tumour cells. Since initial studies in Drosophila melanogaster were instrumental in defining Hippo signalling, the machinery was named after the central Ste20-like kinase...

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Bibliografiske detaljer
Hovedforfatter: Hergovich, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398126/
https://ncbi.nlm.nih.gov/pubmed/22260677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20110619
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