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Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling

The metazoan Hippo pathway is an essential tumour suppressor signalling cascade that ensures normal tissue growth by co-ordinating cell proliferation, cell death and cell differentiation. Over the past years, various genetic and biochemical studies in Drosophila and mammals have defined a conserved...

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Detalhes bibliográficos
Autor principal: Hergovich, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849777/
https://ncbi.nlm.nih.gov/pubmed/23985307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-32
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