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Protein Kinases of the Hippo Pathway: Regulation and Substrates

The “Hippo” signaling pathway has emerged as a major regulator of cell proliferation and survival in metazoans. The pathway, as delineated by genetic and biochemical studies in Drosophila, consists of a kinase cascade regulated by cell-cell contact and cell polarity that inhibits the transcriptional...

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Detalhes bibliográficos
Main Authors: Avruch, Joseph, Zhou, Dawang, Fitamant, Julien, Bardeesy, Nabeel, Mou, Fan, Barrufet, Laura Regué
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489012/
https://ncbi.nlm.nih.gov/pubmed/22898666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.07.002
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