Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers

BACKGROUND: Next-generation sequencing of matched tumor and normal biopsy pairs has become a technology of paramount importance for precision cancer treatment. Sequencing costs have dropped tremendously, allowing the sequencing of the whole exome of tumors for just a fraction of the total treatment...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:BMC Bioinformatics
Autori principali: Hofmann, Ariane L., Behr, Jonas, Singer, Jochen, Kuipers, Jack, Beisel, Christian, Schraml, Peter, Moch, Holger, Beerenwinkel, Niko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209852/
https://ncbi.nlm.nih.gov/pubmed/28049408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1417-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi