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The Role of Age on Dose Limiting Toxicities (DLTs) in Phase I Dose-escalation Trials

PURPOSE: Elderly oncology patients are not enrolled in early phase trials in proportion to the numbers of geriatric patients with cancer. There may be concern that elderly patients will not tolerate investigational agents as well as younger patients resulting in a disproportionate number of dose-lim...

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書目詳細資料
發表在:Clin Cancer Res
Main Authors: Schwandt, A, Harris, P. J., Hunsberger, S., Deleporte, A., Smith, G. L., Vulih, D., Anderson, B. D., Ivy, S. P.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207798/
https://ncbi.nlm.nih.gov/pubmed/25028396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0866
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