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The Role of Age on Dose Limiting Toxicities (DLTs) in Phase I Dose-escalation Trials

PURPOSE: Elderly oncology patients are not enrolled in early phase trials in proportion to the numbers of geriatric patients with cancer. There may be concern that elderly patients will not tolerate investigational agents as well as younger patients resulting in a disproportionate number of dose-lim...

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Publicat a:Clin Cancer Res
Autors principals: Schwandt, A, Harris, P. J., Hunsberger, S., Deleporte, A., Smith, G. L., Vulih, D., Anderson, B. D., Ivy, S. P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207798/
https://ncbi.nlm.nih.gov/pubmed/25028396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0866
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