Haplotypes of the HLA-G 3’ Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially

The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in cancer invasion and acceptance of allografts. The 5’ and 3’ regulatory regions of the HLA-G gene are polymorphic and balancing selection probably maintains this variability. It is proposed that nucleotide variati...

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Udgivet i:PLoS One
Main Authors: Poras, Isabelle, Yaghi, Layale, Martelli-Palomino, Gustavo, Mendes-Junior, Celso T., Muniz, Yara Costa Netto, Cagnin, Natalia F., Sgorla de Almeida, Bibiana, Castelli, Erick C., Carosella, Edgardo D., Donadi, Eduardo A., Moreau, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207740/
https://ncbi.nlm.nih.gov/pubmed/28045999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169032
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