Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population.

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher variability at regulatory 5' and 3' untranslated (3'UTR) regions. At least three 3'UTR polymorphic sites have been associated wit...

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Detalhes bibliográficos
Principais autores: Gustavo Martelli-Palomino, Joao A Pancotto, Yara C Muniz, Celso T Mendes-Junior, Erick C Castelli, Juliana D Massaro, Irene Krawice-Radanne, Isabelle Poras, Vera Rebmann, Edgardo D Carosella, Nathalie Rouas-Freiss, Philippe Moreau, Eduardo A Donadi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3808361?pdf=render
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