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Enhancement of IUdR Radiosensitization by Low-Energy Photons Results from Increased and Persistent DNA Damage
Low-energy X-rays induce Auger cascades by photoelectric absorption in iodine present in the DNA of cells labeled with 5-iodo-2’-deoxyuridine (IUdR). This photoactivation therapy results in enhanced cellular sensitivity to radiation which reaches its maximum with 50 keV photons. Synchrotron core fac...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207426/ https://ncbi.nlm.nih.gov/pubmed/28045991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168395 |
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