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Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

Blood vessels are part of the stem cell niche in the developing cerebral cortex, but their in vivo role in controlling the expansion and differentiation of neural stem cells (NSCs) in development has not been studied. Here, we report that relief of hypoxia in the developing cerebral cortex by ingrow...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lange, Christian, Turrero Garcia, Miguel, Decimo, Ilaria, Bifari, Francesco, Eelen, Guy, Quaegebeur, Annelies, Boon, Ruben, Zhao, Hui, Boeckx, Bram, Chang, Junlei, Wu, Christine, Le Noble, Ferdinand, Lambrechts, Diether, Dewerchin, Mieke, Kuo, Calvin J, Huttner, Wieland B, Carmeliet, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207321/
https://ncbi.nlm.nih.gov/pubmed/26856890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592372
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