Incomplete and transitory decrease of glycolysis: A new paradigm for anti-angiogenic therapy?

During vessel sprouting, a migratory endothelial tip cell guides the sprout, while proliferating stalk cells elongate the branch. Tip and stalk cell phenotypes are not genetically predetermined fates, but are dynamically interchangeable to ensure that the fittest endothelial cell (EC) leads the vess...

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Main Authors: Schoors, Sandra, Cantelmo, Anna Rita, Georgiadou, Maria, Stapor, Peter, Wang, Xingwu, Quaegebeur, Annelies, Cauwenberghs, Sandra, Wong, Brian W, Bifari, Francesco, Decimo, Ilaria, Schoonjans, Luc, De Bock, Katrien, Dewerchin, Mieke, Carmeliet, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925729/
https://ncbi.nlm.nih.gov/pubmed/24335389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27519
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