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Incomplete and transitory decrease of glycolysis: A new paradigm for anti-angiogenic therapy?

During vessel sprouting, a migratory endothelial tip cell guides the sprout, while proliferating stalk cells elongate the branch. Tip and stalk cell phenotypes are not genetically predetermined fates, but are dynamically interchangeable to ensure that the fittest endothelial cell (EC) leads the vess...

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Bibliografski detalji
Glavni autori: Schoors, Sandra, Cantelmo, Anna Rita, Georgiadou, Maria, Stapor, Peter, Wang, Xingwu, Quaegebeur, Annelies, Cauwenberghs, Sandra, Wong, Brian W, Bifari, Francesco, Decimo, Ilaria, Schoonjans, Luc, De Bock, Katrien, Dewerchin, Mieke, Carmeliet, Peter
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925729/
https://ncbi.nlm.nih.gov/pubmed/24335389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27519
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