Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis

Although the differentiation of oncogenically transformed basal progenitor cells is one of the key steps in prostate tumorigenesis, the mechanisms mediating this cellular process are still largely unknown. Here we demonstrate that an expanded p63(+) and CK5(+) basal/progenitor cell population, induc...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Meng, Ingram, Lishann, Tolosa, Ezequiel J., Vera, Renzo E., Li, Qianjin, Kim, Sungjin, Ma, Yongjie, Spyropoulos, Demetri D., Beharry, Zanna, Huang, Jiaoti, Fernandez-Zapico, Martin E., Cai, Houjian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207270/
https://ncbi.nlm.nih.gov/pubmed/27760825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753129
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