Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis

Although the differentiation of oncogenically transformed basal progenitor cells is one of the key steps in prostate tumorigenesis, the mechanisms mediating this cellular process are still largely unknown. Here we demonstrate that an expanded p63(+) and CK5(+) basal/progenitor cell population, induc...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Wu, Meng, Ingram, Lishann, Tolosa, Ezequiel J., Vera, Renzo E., Li, Qianjin, Kim, Sungjin, Ma, Yongjie, Spyropoulos, Demetri D., Beharry, Zanna, Huang, Jiaoti, Fernandez-Zapico, Martin E., Cai, Houjian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207270/
https://ncbi.nlm.nih.gov/pubmed/27760825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753129
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