Family-wide Structural Characterization and Genomic Comparisons Decode the Diversity-oriented Biosynthesis of Thalassospiramides by Marine Proteobacteria

The thalassospiramide lipopeptides have great potential for therapeutic applications; however, their structural and functional diversity and biosynthesis are poorly understood. Here, by cultivating 130 Rhodospirillaceae strains sampled from oceans worldwide, we discovered 21 new thalassospiramide an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Weipeng, Lu, Liang, Lai, Qiliang, Zhu, Beika, Li, Zhongrui, Xu, Ying, Shao, Zongze, Herrup, Karl, Moore, Bradley S., Ross, Avena C., Qian, Pei-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207150/
https://ncbi.nlm.nih.gov/pubmed/27875306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756858
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