Biosynthetic Multitasking Facilitates Thalassospiramide Structural Diversity in Marine Bacteria

Thalassospiramides A and B are immunosuppressant cyclic lipopeptides first reported from the marine α-proteobacterium Thalassospira sp. CNJ-328. We describe here the discovery and characterization of an extended family of 14 new analogues from four Tistrella and Thalassospira isolates. These potent...

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Main Authors: Ross, Avena C., Xu, Ying, Lu, Liang, Kersten, Roland D., Shao, Zongze, Al-Suwailem, Abdulaziz M., Dorrestein, Pieter C., Qian, Pei-Yuan, Moore, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563429/
https://ncbi.nlm.nih.gov/pubmed/23270364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3119674
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