Family-wide Structural Characterization and Genomic Comparisons Decode the Diversity-oriented Biosynthesis of Thalassospiramides by Marine Proteobacteria

The thalassospiramide lipopeptides have great potential for therapeutic applications; however, their structural and functional diversity and biosynthesis are poorly understood. Here, by cultivating 130 Rhodospirillaceae strains sampled from oceans worldwide, we discovered 21 new thalassospiramide an...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Weipeng, Lu, Liang, Lai, Qiliang, Zhu, Beika, Li, Zhongrui, Xu, Ying, Shao, Zongze, Herrup, Karl, Moore, Bradley S., Ross, Avena C., Qian, Pei-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207150/
https://ncbi.nlm.nih.gov/pubmed/27875306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756858
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