A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity

Nitric oxide (NO) is integral to macrophage cytotoxicity against tumors due to its ability to induce iron release from cancer cells. However, the mechanism for how activated macrophages protect themselves from endogenous NO remains unknown. We previously demonstrated by using tumor cells that glutat...

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Опубликовано в: :J Biol Chem
Главные авторы: Lok, Hiu Chuen, Sahni, Sumit, Jansson, Patric J., Kovacevic, Zaklina, Hawkins, Clare L., Richardson, Des R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207136/
https://ncbi.nlm.nih.gov/pubmed/27866158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763714
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