A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity

Nitric oxide (NO) is integral to macrophage cytotoxicity against tumors due to its ability to induce iron release from cancer cells. However, the mechanism for how activated macrophages protect themselves from endogenous NO remains unknown. We previously demonstrated by using tumor cells that glutat...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Lok, Hiu Chuen, Sahni, Sumit, Jansson, Patric J., Kovacevic, Zaklina, Hawkins, Clare L., Richardson, Des R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207136/
https://ncbi.nlm.nih.gov/pubmed/27866158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763714
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