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Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter

The plasmalemmal monoamine transporters clear the extracellular space from their cognate substrates and sustain cellular monoamine stores even during neuronal activity. In some instances, however, the transporters enter a substrate-exchange mode, which results in release of intracellular substrate....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hasenhuetl, Peter S., Freissmuth, Michael, Sandtner, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207061/
https://ncbi.nlm.nih.gov/pubmed/27756841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753319
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