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Dual Action of Zn(2+) on the Transport Cycle of the Dopamine Transporter
The dopamine transporter shapes dopaminergic neurotransmission by clearing extracellular dopamine and by replenishing vesicular stores. The dopamine transporter carries an endogenous binding site for Zn(2+), but the nature of the Zn(2+)-dependent modulation has remained elusive: both, inhibition and...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692231/ https://ncbi.nlm.nih.gov/pubmed/26504078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.688275 |
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