Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes

Rare variants enriched for functions in chromatin regulation and neuronal synapses have been linked to autism. How chromatin and DNA methylation interact with environmental exposures at synaptic genes in autism etiologies is currently unclear. Using whole genome bisulfite sequencing in brain tissue...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Dunaway, Keith W., Islam, M. Saharul, Coulson, Rochelle L., Lopez, S. Jesse, Ciernia, Annie Vogel, Chu, Roy G., Yasui, Dag H., Pessah, Isaac N., Lott, Paul, Mordaunt, Charles, Meguro-Horike, Makiko, Horike, Shin-ichi, Korf, Ian, LaSalle, Janine M.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206988/
https://ncbi.nlm.nih.gov/pubmed/27974215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.058
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