UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons

The dysregulation of genes in neurodevelopmental disorders that lead to social and cognitive phenotypes is a complex, multilayered process involving both genetics and epigenetics. Parent-of-origin effects of deletion and duplication of the 15q11-q13 locus leading to Angelman, Prader-Willi, and Dup15...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Lopez, S. Jesse, Dunaway, Keith, Islam, M. Saharul, Mordaunt, Charles, Vogel Ciernia, Annie, Meguro-Horike, Makiko, Horike, Shin-ichi, Segal, David J., LaSalle, Janine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788436/
https://ncbi.nlm.nih.gov/pubmed/28925810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1376151
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