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Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes

Rare variants enriched for functions in chromatin regulation and neuronal synapses have been linked to autism. How chromatin and DNA methylation interact with environmental exposures at synaptic genes in autism etiologies is currently unclear. Using whole genome bisulfite sequencing in brain tissue...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Dunaway, Keith W., Islam, M. Saharul, Coulson, Rochelle L., Lopez, S. Jesse, Ciernia, Annie Vogel, Chu, Roy G., Yasui, Dag H., Pessah, Isaac N., Lott, Paul, Mordaunt, Charles, Meguro-Horike, Makiko, Horike, Shin-ichi, Korf, Ian, LaSalle, Janine M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206988/
https://ncbi.nlm.nih.gov/pubmed/27974215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.058
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