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A Genetically Encoded Allysine for the Synthesis of Proteins with Site-specific Lysine Dimethylation
Using the amber suppression approach, N(ε)-(4-azidobenzoxycarbonyl)-δ, ε-dehydrolysine, an allysine precursor is genetically encoded in E. coli. Its genetic incorporation followed by two sequential biocompatible reactions allows convenient synthesis of proteins with site-specific lysine dimethylatio...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206893/ https://ncbi.nlm.nih.gov/pubmed/27910233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609452 |
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