Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

We have reported that the Toll-like receptor 9 (TLR9) signaling pathway plays an important role in the development of pressure overload-induced inflammatory responses and heart failure. However, its role in cardiac remodeling after myocardial infarction has not been elucidated. TLR9-deficient and co...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Omiya, Shigemiki, Omori, Yosuke, Taneike, Manabu, Protti, Andrea, Yamaguchi, Osamu, Akira, Shizuo, Shah, Ajay M., Nishida, Kazuhiko, Otsu, Kinya
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
Soggetti:
Integrative Cardiovascular Physiology and Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206340/
https://ncbi.nlm.nih.gov/pubmed/27769998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00481.2016
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