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Na(+)-K(+)-Cl(−) cotransporter (NKCC) maintains the chloride gradient to sustain pacemaker activity in interstitial cells of Cajal
Interstitial cells of Cajal (ICC) generate electrical slow waves by coordinated openings of ANO1 channels, a Ca(2+)-activated Cl(−) (CaCC) conductance. Efflux of Cl(−) during slow waves must be significant, as there is high current density during slow-wave currents and slow waves are of sufficient m...
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| Yayımlandı: | Am J Physiol Gastrointest Liver Physiol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206290/ https://ncbi.nlm.nih.gov/pubmed/27742704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00277.2016 |
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