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Intracellular Ca(2+) release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal

Interstitial cells of Cajal (ICC) provide pacemaker activity in gastrointestinal muscles that underlies segmental and peristaltic contractions. ICC generate electrical slow waves that are due to large-amplitude inward currents resulting from anoctamin 1 (ANO1) channels, which are Ca(2+)-activated Cl...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Zhu, Mei Hong, Sung, Tae Sik, O'Driscoll, Kate, Koh, Sang Don, Sanders, Kenton M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398848/
https://ncbi.nlm.nih.gov/pubmed/25631870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00360.2014
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