4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1

Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) integrates signals from growth factors, cellular energy levels, stress and amino acids to control cell growth and proliferation through regulating translation, autophagy and metabolism. Here we determined the cryo-electron microscopy structur...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Yang, Huirong, Wang, Jia, Liu, Mengjie, Chen, Xizi, Huang, Min, Tan, Dan, Dong, Meng-Qiu, Wong, Catherine C. L., Wang, Jiawei, Xu, Yanhui, Wang, Hong-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5205667/
https://ncbi.nlm.nih.gov/pubmed/27909983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0346-6
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