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Novel compound heterozygous mutations in ABCA4 in a Chinese pedigree with Stargardt disease

PURPOSE: Stargardt disease (STGD) is a common macular dystrophy in juveniles that is commonly inherited as an autosomal recessive trait. Mutations in five genes (ABCA4, PROM1, ELOVL4, BEST1, and PRPH2) have been reported to be associated with STGD. In the present study, we aimed to identify the path...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Zhang, Jianping, Qi, Anhui, Wang, Xi, Pan, Hong, Mo, Haiming, Huang, Jiwei, Li, Honghui, Chen, Zhenwen, Wei, Meirong, Wang, Binbin
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204459/
https://ncbi.nlm.nih.gov/pubmed/28050124
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