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Compound heterozygous mutations in CFTR causing CBAVD in Chinese pedigrees

BACKGROUND: Congenital bilateral absence of the vas deferens (CBAVD) is an important cause of obstructive azoospermia and male infertility. Mutations of CFTR caused the majority of CBAVD cases, and ADGRG2 was recently identified as a new pathogenic gene. Yet, most of the genetic evidence came from s...

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Publicado en:Mol Genet Genomic Med
Autores principales: Yang, Bin, Wang, Xi, Zhang, Wei, Li, Hongjun, Wang, Binbin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305631/
https://ncbi.nlm.nih.gov/pubmed/30450785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.486
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