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Compound heterozygous mutations in CFTR causing CBAVD in Chinese pedigrees

BACKGROUND: Congenital bilateral absence of the vas deferens (CBAVD) is an important cause of obstructive azoospermia and male infertility. Mutations of CFTR caused the majority of CBAVD cases, and ADGRG2 was recently identified as a new pathogenic gene. Yet, most of the genetic evidence came from s...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Yang, Bin, Wang, Xi, Zhang, Wei, Li, Hongjun, Wang, Binbin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305631/
https://ncbi.nlm.nih.gov/pubmed/30450785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.486
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